How Your Mitochondria Boost Your Energy

Feeling energized isn’t just about getting a good night’s sleep or sipping on caffeine—it’s deeply rooted in the body’s cellular processes, especially the function of our mitochondria. Often called the “powerhouses” of cells, mitochondria generate the energy required for every action, from thinking and breathing to running and lifting. One of the most effective ways to enhance mitochondrial function is through regular movement, which stimulates mitochondrial growth and efficiency, ultimately increasing both your energy levels and resilience.

The Science of Mitochondrial Energy Production

Mitochondria produce adenosine triphosphate (ATP), the molecule responsible for storing and transferring energy within cells. ATP powers virtually every cellular function, making it the body’s main energy currency. During physical activity, muscles require a rapid ATP supply, which places extra demand on mitochondria. In response, the body initiates mitoplasticity—an adaptive process where mitochondria increase in number, size, and efficiency, enabling cells to meet higher energy demands​​.

Regular movement also boosts the density of mitochondrial cristae, the membrane folds where ATP production takes place. With more cristae, mitochondria can produce more energy. Additionally, as mitochondria become more efficient at processing oxygen during exercise, they generate less reactive oxygen species (ROS), reducing oxidative stress and enhancing cellular health​.

How Movement Increases Energy

Physical activity not only stimulates mitogenesis (the creation of new mitochondria) but also improves existing mitochondria’s ability to generate ATP. Here’s how movement influences mitochondrial function and overall energy:

  1. Enhanced Oxygen Utilization
    Physical exercise, especially aerobic activities like running or swimming, trains the body to deliver and utilize oxygen more efficiently. The cardiovascular system adapts by increasing red blood cells and capillary density, improving oxygen flow to muscles. Mitochondria in these oxygen-rich environments become more effective at producing ATP, resulting in more sustainable energy and endurance​​.

  2. Improved Fat and Glucose Metabolism
    Exercise increases enzymes involved in fat and glucose metabolism within mitochondria. With regular movement, mitochondria adapt to use fats and sugars more efficiently, leading to sustained energy levels throughout the day. This metabolic flexibility means you rely less on blood sugar spikes, which can lead to energy crashes, and more on a stable, sustained energy supply from stored fats​.

  3. Reduced Oxidative Stress
    Enhanced mitochondrial efficiency reduces the amount of ROS produced during ATP synthesis, thereby minimizing oxidative damage to cells. Physical activity also triggers the release of antioxidants that help counteract ROS. This combination of reduced ROS production and increased antioxidant defense helps maintain energy levels and protect against cellular aging​.

Practical Steps to Boost Energy Through Movement

You don’t need to be an elite athlete to reap the benefits of improved mitochondrial function. Here’s how to incorporate movement for lasting energy:

  1. Engage in Regular Aerobic Exercise
    Activities like brisk walking, cycling, or swimming support cardiovascular health and stimulate mitogenesis. Aim for at least 150 minutes of moderate aerobic exercise each week to increase mitochondrial efficiency and support long-term energy production.

  2. Incorporate Resistance Training
    Contrary to popular belief, strength training also benefits mitochondrial health. Resistance exercises such as weightlifting or bodyweight movements improve muscle strength and stimulate mitochondrial adaptation, making them efficient for boosting energy. Studies have shown that resistance training can increase mitochondrial respiration and oxygen usage just as effectively as aerobic exercise​​.

  3. Practice Interval Training
    High-intensity interval training (HIIT) involves short bursts of intense activity followed by rest. This type of training not only increases mitochondrial density but also trains the body to rapidly switch between energy systems, promoting metabolic flexibility. HIIT can be an efficient way to boost mitochondrial function in shorter workout sessions.

  4. Move Consistently Throughout the Day
    Staying active doesn’t mean only structured exercise sessions; regular movement throughout the day also supports mitochondrial health. Take short walks, stretch, or use a standing desk to reduce sedentary time. Every bit of movement signals your mitochondria to stay active and engaged, keeping energy levels steady.

Conclusion: Move to Power Up Your Life

Incorporating movement into your daily routine does more than just maintain physical health—it optimizes cellular energy production by enhancing mitochondrial function. By exercising regularly, practicing interval and strength training, and staying active throughout the day, you can harness the power of mitochondria to boost your energy and resilience. With more efficient mitochondria powering every cell, you’ll not only feel more energetic but also improve your health and performance across all areas of life.

This article is based on my Powerhouse book. If you want to learn more about healthy peak performance you can order the book here.

Greg Wells PhD

For Dr. Greg Wells, health and performance, particularly under extreme conditions, are personal and professional obsessions. As a scientist and physiologist, he has dedicated his career to making the science of human limits understandable and actionable. Dr. Wells has spoken to audiences all over the world at events such as TEDx and The Titan Summit, where he has shared the stage with Robin Sharma, Richard Branson, Steve Wozniak and Deepak Chopra.

For over 25 years, Dr. Wells has worked with some of the highest-performing individuals on the planet, including Olympic and World champions, and with organizations ranging from General Electric to BMO, Deloitte, KPMG, BMW, Audi, Sysco Foods, YPO and Air Canada. He is also committed to inspiring children and young adults through his close working relationship with school boards and independent schools.

A veteran endurance athlete, Dr. Wells has participated in the grueling Nanisivik Marathon 600 miles north of the Arctic Circle, Ironman Canada and the Tour D’Afrique, an 11,000 km cycling race that is the longest in the world. He is also a travel and expedition adventurer who has journeyed through every imaginable terrain and conditions in over 50 countries around the world.

Dr. Wells is author of three best-selling books – Superbodies, The Ripple Effect, and The Focus Effect – and hosted the award-winning Superbodies series, which aired on Olympic broadcasts worldwide in 2010 and 2012.

Dr. Wells has a PhD in Physiology, served as an Associate Professor of Kinesiology at the University of Toronto and is an exercise medicine researcher at the Hospital for Sick Children in Toronto.

He is the CEO and founder of The Wells Group, a global consulting firm committed to achieving the moonshot of helping teams, schools and businesses become places where people get healthy, perform optimally and ultimately - reach their potential.

http://www.drgregwells.com
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